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Lipoic Acid

What Researchers Say

Dr. Tory Hagen, in Mitochondrial Decay in Aging.
“We’re finding – and others are, too – that the R(+)-form – the natural form – is much more powerful than the racemic mixture ... Hopefully ... companies are going to be producing on more of a clinical scale the R(+)-form of lipoic acid, because we’re finding very significant effects using this, as opposed to the racemic mixture.”

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Dr. Ryan Streeper and colleagues, in The American Journal of Physiology.
“We have presented in this study new information indicating that this enhancement of glucose metabolism is sterospecific, with the R(+)-enantiomer being much more effective than the S(-)- enantiomer.”

Dr. Bruce Ames, in Strategies for Engineered Negligible Senescence.
“Lipoic acid sold in a health food store is a synthetic mixture, a racemic mixture. And R[+]- is the natural form and S[-]- is an unnatural one ... And in our hands R[+]-works and S[-]- doesn’t.”

Dr. Lester Packer and colleagues, in Free Radical Biology and Medicine.
“R[+]-LA [that is, R(+)-lipoic acid], and not a racemic mixture of R[+]-and S[-]- LA, should be considered a choice for therapeutic applications.”

Dr. Guido Zimmer and colleagues, in Methods in Enzymoogy.
“The S[-]-enantiomer … part of the racemate, which is present as about a 50% impurity, needs to be eliminated.”


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Please consult with a health care professional before starting any supplementation program. The information contained on this site is general in nature and Company does not take any responsibility for any errors that may appear. Company has made every attempt to make the information as accurate as possible. However, Company does not warrant its accuracy. Please note that the statements on this web site have not been evaluated by the FDA.