U.S. Pharmacopeia 25 through Second Supplement Analysis: Specific Rotation
Dates Analyzed: 09-18-02 to 09-19-02
Sample ID: 08/02 R-ALA H13 08-/04
Result: +98°
According to the Merck Index the specific rotation of the raw material is +104°. The capsule contents, at least the lipoic acid, went into solution rather quickly.
Considering that the lipoic acid content per capsule can vary by at least as much as 10%, the result of +98° would appear to confirm that it is R-ALA and not a mixture or the levorotatory.
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